Cart
sales@molnova.com
MJ33 lithium salt
CAS No. 1007476-63-2
MJ33 lithium salt( —— )
Catalog No. M35038 CAS No. 1007476-63-2
MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, a fluorinated phospholipid analog that inhibits the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx6), and is used in the study of acute lung injury.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMJ33 lithium salt
-
NoteResearch use only, not for human use.
-
Brief DescriptionMJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, a fluorinated phospholipid analog that inhibits the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx6), and is used in the study of acute lung injury.
-
DescriptionMJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetROS
-
RecptorROS
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1007476-63-2
-
Formula Weight498.48
-
Molecular FormulaC22H43F3LiO6P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=P(OC)(OC(COCC(F)(F)F)COCCCCCCCCCCCCCCCC)[O-].[Li+]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fisher AB, Dodia C, Chander A, Jain M. A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung. Biochem J. 1992 Dec 1;288 ( Pt 2)(Pt 2):407-11. ?
molnova catalog
related products
-
Benzoyl peroxide
A peroxide derivative that has been used topically for BURNS and as a dermatologic agent in the treatment of ACNE and POISON IVY DERMATITIS.
-
F-1
?F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.?F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.
-
DMNQ
DMNQ is a 14-naphthoquinone that acts as a redox-cycling agent typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS generation
